Amputations Side Effects: Invokana Only, Or Jardiance, Farxiga, And Other SGLT2 Inhibitors Diabetes Drugs, Too?

Increasing Degree Of Acknowledgement In Medical Literature That Toe, Foot, And Leg Amputations Are Drug-Class Side Effects

 

(Posted by Tom Lamb at DrugInjuryWatch.com)

 

We have been following developments in the medical realm concerning the drug safety issue of whether the toes, feet, and legs amputations side effects associated with Invokana (canagliflozin) are found, also, with Jardiance (empagliflozin), Farxiga (dapagliflozin), and other diabetes medicines in the sodium-glucose co-transporter-2 (SGLT2) inhibitors class of drugs. 

There seems to be an increasing degree of acknowledgement in the medical literature that these lower limb amputations are drug-class side effects of SGLT2 inhibitor diabetes medicines such as Jardiance and Farxiga in addition to Invokana.

For example, from this recent Medscape news report, "Canagliflozin (Invokana) Gets FDA Nod for CV Protection" there is this summary-type statement:

As with other SGLT2 inhibitors, [Invokana (canagliflozin)] may increase the risk of lower-limb amputations. The FDA added a boxed warning to the [Invokana (canagliflozin)] label last year.   [Emphasis added]

For on overview of how and why there is an apparent elevated risk of below-knee lower extremity (BKLE) amputations for Jardiance as well as Farxiga and other SGLT2 inhibitors diabetes drugs, you can review one of our brief pieces about this topic on our Drug Injury Law site:

• Lower Limbs Amputations Are SGLT-2 Inhibitors Drug-Class Side Effects
• Increased Risks Of Lower-Limb Amputations For Farxiga And Jardiance
• Invokana, Jardiance, And Farxiga Have Increased Risks Of Amputations
• Jardiance – Lower Limb Amputations Drug Safety Issue Remains Uncertain

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And if you want some more in-depth information on lower limb amputations being side effects of Jardiance, Farxiga, and similar diabetes drugs, you can read one or more of these four articles published earlier here on Drug Injury Watch:

1. Amputations Are SGLT-2 Inhibitors Drug-Class Side Effects It Now Appears, According To New Medical Evidence 
2. Invokana / Jardiance / Farxiga: Increased Risks Of Lower-Limb Amputations Compared To Another Class Of Diabetes Drugs 
3. Some Newer Diabetes Drugs Linked To Lower Limb Amputations: "Significantly Increased Risk" 
4. Jardiance - Amputations Drug Safety Issue Remains Uncertain Due To Admitted "inherent limitations of... post hoc analyses"

Over the past year we have been investigating drug injury lawsuits for patients who have had lower extremity amputations (legs, feet, toes) while using Invokana, Jardiance, Farxiga, or one of the other SGLT-2 inhibitors.   And given the direction that the medical literature appears to being going in, we will continue to do so.

DrugInjuryLaw.com: Medical & Legal Information About Drug Side Effects  (All website content by attorney Tom Lamb)

Drug Injury Case Evaluation - Free. Confidential. No Obligation.  (Case review done by attorney Tom Lamb)