Written by: Heather Helmendach, Legal Assistant
Law Offices of Thomas J. Lamb, P.A.
As previously discussed in my articles, "Breast Implants Linked to Rare Lymphoma Blood Cancer" and "Breast Implant Lymphoma: Causes Uncertain, but Costs Undeniable, the FDA recently updated their 2011 report of the association between breast implants and anaplastic large-cell lymphoma (ALCL), providing additional information on this rare form of cancer that has affected over 359 women around the world.
A New York Times article recently relayed the stories of several women who were diagnosed with BIA-ALCL, the current statistics in the U.S. and abroad, as well as possible theories for how BIA-ALCL may develop in women who have had breast implants, particularly textured ones.
The article provides the following information on the theories with input from Dr. Mark W. Clemens II, a plastic surgeon and an expert on the disease at the University of Texas MD Anderson Cancer Center in Houston:
What exactly causes the disease is not known. One theory is that bacteria may cling to textured implants and form a coating called a biofilm that stirs up the immune system and causes persistent inflammation, which may eventually lead to lymphoma. The idea is medically plausible, because other types of lymphoma stem from certain chronic infections. Professional societies for plastic surgeons recommend special techniques to avoid contamination in the operating room when implants are inserted.
“It could also just be the immune system response to some component of the texturing,” Dr. Clemens said. The rough surface may be irritating or abrasive. Allergan implants seem to be associated with more cases than other types, possibly because they are more deeply textured and have more surface area for bacteria to stick to, he said.
A Medical Xpress article confirms the former theory, stating,
We knew that growth of bacteria on the surface of breast implants can, over time, cause an increase in stimulation of the lymphocytes, turning them into BIA-ALCL. However, we now know textured implants, which have a higher surface area, carry a significantly higher risk of BIA-ALCL. This is because these high surface area textured implants act as a passive conduit for the growth and proliferation of bacteria.
They also reference Allergan implants, and point out that 58.7% of BIA-ALCL cases involve Allergan Biocell salt loss textured implants.
An article by 9News provides additional information on this theory:
9NEWS understands clusters of cases of women who have developed ALCL after being operated on by the same surgeon have been reported.
The cancer is believed to develop from bacteria getting onto an implant before it’s inserted into a patient’s chest. Typically, it grows in a capsule of fluid around the implant and is diagnosed on average 7.5 years after surgery – although it can take decades.
Additionally, this article mentions that Professor Anand Deva, head of cosmetic, plastic and reconstructive surgery at Macquarie University in Sydney, and his research colleagues have developed a "14-point plan for surgeons to prevent ALCL."
From a legal standpoint, this development is of particular interest, and raises some important questions. Who should be held responsible for the suffering that results from hundreds of BIA-ALCL diagnoses?
If bacterial contamination of the breast implants prior to insertion is the cause of BIA-ALCL, can the blame be placed on the manufacturers of the breast implants? The facilities in which the implant procedures are performed? The surgeons themselves? Do all parties share in the responsibility?
We will continue to monitor the medical literature concerning the association of breast implants with BIA-ALCL to look for new developments and better determine who should be held accountable for the harm that has befallen women who have received this diagnosis.
In the meantime, we invite you to visit the information page on our website if you would like to learn more about BIA-ACL, or complete our free case evaluation form if you or someone you know has been diagnosed with BIA-ALCL as a result of breast implants.
Previous articles on this topic:
- Breast Implant Lymphoma: Causes Uncertain, but Costs Undeniable
- Breast Implants Linked to Rare Lymphoma Blood Cancer