Quoted from http://prescriptions.blogs.nytimes.com/2011/10/26/study-yaz-has-higher-risks-of-blood-clots/
Study: Yaz Has Higher Risks of Blood Clots
By DUFF WILSON
October 26, 2011, 12:53 pm
A new study of 1.3 million Danish women over nine years adds to the evidence that some newer birth-control pills, including the best-seller Yaz, have a higher risk of causing potentially dangerous blood clots.
Newer pills containing drospirenone, a synthetic hormone, were linked to a six-fold increase in the risk of venous thromboembolism, which is the formation of clots in the lower leg or thigh that can break loose and travel to the lungs.
That risk was compared with a three-fold increase in women using older contraceptives containing the synthetic hormone levonorgestrel. The study was published Tuesday on the Web site of BMJ, formerly known as the British Medical Journal.
A BMJ editorial added, “It is crucial, however, not to exaggerate the risk — oral contraceptives are remarkably safe and may confer important long-term benefits in relation to cancer and mortality.”
The Food and Drug Administration is already studying the possible increased risk of blood clots with pills containing the drospirenone. The F.D.A. says its preliminary results suggest a 1.5-fold increased risk compared with other hormonal contraceptives, to about 10 women in 10,000 from 6 women in 10,000.