Quoted from http://www.reuters.com/article/2011/06/16/us-drugs-fda-chantix-idUSTRE75F4PW20110616
Pfizer stop-smoking pill raises heart risk: FDA
WASHINGTON | Thu Jun 16, 2011 12:08pm EDT
WASHINGTON (Reuters) - Pfizer's stop-smoking drug Chantix can lead to a small increase in cardiovascular problems such as heart attacks for patients who already have cardiovascular disease, U.S. drug regulators said on Thursday.
The Food and Drug Administration is changing the label for Chantix after reviewing the results of a clinical trial.
An independent randomized trial of 700 smokers with cardiovascular disease who were treated with Chantix or a placebo showed that Chantix was effective in helping patients quit smoking for as long as one year.
However, patients who took the pill were also slightly more likely to have a heart attack or other adverse cardiovascular event versus patients on a placebo.
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