Quoted from http://www.cbc.ca/health/story/2010/11/18/avandia-warnings-canada.html
Diabetes drug Avandia gets heart warnings
Last Updated: Thursday, November 18, 2010 | 1:33 PM ET
The diabetes drug Avandia now comes with warnings in Canada about heart risks, the drug's manufacturer said Thursday.
Canadians taking Avandia should make an appointment with their doctor as soon as possible about their treatment because of the Type 2 diabetes drug's potential risks, but not stop treatment abruptly, GlaxoSmithKline said.
The company, in consultation with Health Canada, announced new restrictions on the use of drugs containing rosiglitazone, such as Avandia, in people with Type 2 diabetes.
Package warnings say the drugs may increase the risk of serious heart problems, including heart failure, chest pain, heart attack and fluid retention.
The drugs should not be used in people who have or have had heart problems. People should talk to their doctor about other options before using the drug.
Based on Health Canada's review of recent data suggesting a higher risk of heart-related problems in patients treated with Avandia, the company has updated information for consumers and health-care professionals, including new restrictions on using the drug.