Quoted from http://health.usnews.com/health-news/family-health/heart/articles/2010/10/12/cancer-fighting-bone-drugs-might-raise-stroke-risk.html
Cancer-Fighting Bone Drugs Might Raise Stroke Risk
But IV bisphosphonates can also benefit patients, researchers note
Posted: October 12, 2010
By Amanda Gardner
TUESDAY, Oct. 12 (HealthDay News) -- A new study finds that cancer patients treated with bisphosphonate drugs such as Aredia or Zometa to reduce or delay bone complications from cancer may be at higher risk for the irregular heartbeat known as atrial fibrillation and for a related event, stroke.
In atrial fibrillation, the upper chambers of the heart beat chaotically, causing blood to pool and increasing the potential of clots, stroke, heart failure and death.
However, the bump up in risk with bisphosphonates was "relatively modest," said Dr. James Goodwin, senior author of a paper appearing online Oct. 12 in the Journal of Clinical Oncology.
At relatively low doses, bisphosphonates have been widely used for about three decades to treat osteoporosis, mainly in older women.