Quoted from http://www.reuters.com/article/rbssHealthcareNews/idUSN2628355520090826
J&J strengthens warning on HIV drug
WASHINGTON, Aug 26 (Reuters) - Johnson & Johnson has strengthened a warning about serious skin reactions in patients treated with the company's HIV drug Intelence, U.S. regulators and the company said on Wednesday.
J&J's Tibotec Therapeutics unit updated the warning after reports of one death from a skin reaction known as toxic epidermal necrolysis, and another case of liver failure from a severe reaction, said Tibotec spokeswoman Pam Van Houten. The patient with liver failure recovered.
Intelence has included a warning about the risk of severe skin reactions since it was launched in January 2008, Van Houten said. In clinical trials, the rate of serious skin or allergic reactions was less than 0.1 percent, she said.
Intelence should be immediately discontinued if signs of severe skin or allergic reactions, Tibotec said in a letter to doctors.
The Tibotec letter was posted here