Most Of These Patients Did Not Experience Any Kidney Or Renal Problems Before Developing CKD Linked To PPI Heartburn Drugs Or Reflux Medicines
A recent medical study done by medical researchers in St. Louis, Missouri adds to the growing body of evidence which indicates that some popular heartburn drugs and acid reflux medicines like Prevacid, Prilosec, and Nexium can cause serious kidney-related side effects, including these conditions:
Acute Interstitial Nephritis (AIN)
Chronic Kidney Disease (CKD)
End-Stage Renal Disease (ESRD)
Severe Renal Impairment
Kidney / Renal Failure
Acute Kidney Injury
This newest study indicates that more than half of those patients who develop chronic kidney damage (CKD) while using proton pump inhibitors (PPIs) heartburn drugs and acid reflux medicines do not experience acute kidney problems before their CKD diagnosis.
These researchers at Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care System published their findings in this February 2107 article, "Long-term kidney outcomes among users of proton pump inhibitors without intervening acute kidney injury", published in the Kidney International medical journal.
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A February 22, 2017 ScienceDaily news report, "Popular heartburn drugs linked to gradual yet 'silent' kidney damage", provides a good analysis of this recent safety study concerning Nexium, Prevacid, Prilosec, and other PPI heartburn drugs and acid reflux medicines.
From that ScienceDaily news report we get this information:
The onset of acute kidney problems is not a reliable warning sign for clinicians to detect a decline in kidney function among patients taking proton pump inhibitors, said Ziyad Al-Aly, MD, the study's senior author and an assistant professor of medicine at Washington University School of Medicine. "Our results indicate kidney problems can develop silently and gradually over time, eroding kidney function and leading to long-term kidney damage or even renal failure. Patients should be cautioned to tell their doctors if they're taking PPIs and only use the drugs when necessary."...
Over five years of follow up, the researchers found that more than 80 percent of PPI users did not develop acute kidney problems, which often are reversible and are characterized by too little urine leaving the body, fatigue and swelling in the legs and ankles.
However, more than half of the cases of chronic kidney damage and end-stage renal disease associated with PPI use occurred in people without acute kidney problems....
End-stage renal disease occurs when the kidneys can no longer effectively remove waste from the body. In such cases, dialysis or a kidney transplant is needed to keep patients alive.
We are currently investigating possible drug injury lawsuits against the responsible pharmaceutical companies for people who have developed any of the kidney-related medical problems listed above.
Of course, we will continue to monitor the medical literature for developments concerning serious kidney-related side effects of popular heartburn drugs and acid reflux medicines like Nexium, Prilosec, and Prevacid.
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