Quoted from http://www.reuters.com/article/2012/06/27/us-excesssuicide-asthma-idUSBRE85Q11G20120627
No excess suicide risk found with asthma drugs
By Amy Norton
NEW YORK | Wed Jun 27, 2012 11:05am EDT
NEW YORK (Reuters Health) - Despite some reports of suicide among people taking certain asthma drugs, a new study finds no increased risk of attempted suicide among children and young adults on the medications.
In 2008, the Food and Drug Administration (FDA) said it was investigating reports of mood and behavior changes, suicidal thinking and suicide among people taking asthma medications known as leukotriene modifiers.
The drugs include Singulair (known generically as montelukast), Accolate (zafirlukast) and Zyflo (zileuton).
After reviewing clinical trial data on the drugs, the FDA concluded there was no evidence of a link to suicidal behavior. Still, in 2009 the agency asked manufacturers to add a precaution in the drugs' prescribing instructions about reports of suicide and other psychiatric problems.
But single reports of serious effects among medication users can only hint at a problem.
"Case reports don't prove there actually is an association between a drug and an adverse event, because there are so many other factors that could be at work," said Glen T. Schumock, a professor of pharmacy practice at the University of Illinois at Chicago who led the new study.
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